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Unlock EMR insights with physician-trained AI

Maximize capacity for new studies
Enhance patient outcomes
Reduce costs for research
Get actionable insights in record time
Streamline clinical trial enrollment

Synapsis AI is transforming the healthcare landscape with groundbreaking technology that deduces clinical conclusions from EMRs just like a trained physician–only exponentially faster. 

Applications of Synapsis AI in healthcare systems

Dyania’s Synapsis AI is a holistic, disease-agnostic, end-to-end system for delivering insights for enterprise use in oncology, cardiology, autoimmune conditions, and more. Synapsis AI delivers precision, speed, and scalability across a wide range of clinical applications, through screening entire health system populations.

Patient Finder

Reduce the manual burden for clinical trials with automated daily patient pre-screening

Identify and pre-screen patients daily for clinical trial eligibility, accelerating recruitment and reducing timelines. Synapsis AI is an end-to-end system (powered by a proprietary LLM) that continuously reads dynamically-changing patient EMRs to ensure you don’t miss potential participants.

  • Find more candidates, over 15,000x faster.
  • Leverage Dyania’s intuitive app to query specific clinical questions, review EMR data at the individual level, and search for candidates by trial site to automatically identify eligible patients based on trial criteria.
Registries Reporting

Cut costs, save time, & enhance reporting accuracy

Streamline registry population and reporting submissions. Synapsis AI extracts and organizes clinical characteristics, eliminating manual bottlenecks and improving data accuracy. Synapsis AI abstracts and organizes clinical characteristics into field responses, greatly reducing manual effort while improving overall abstraction accuracy.

On average, health systems with ~500,000 patients spend >$5 M annually on staff, performing manual chart abstraction. Medically-specialized personnel are understaffed globally and are notoriously difficult to find/hire.

  • Save up to 50% of these costs by partnering with Dyania.
  • Identify custom, unique fields for reporting to national registries, and use Dyania’s native audit tool to save time and money.
Observational Studies

Help clinical teams identify opportunities to leverage existing data in observational studies 

Uncover clinical characteristics for retrospective and prospective studies with unparalleled accuracy, at scale. Synapsis AI facilitates a deeper understanding of patient populations, fueling evidence-based research.

  • Dyania will partner with healthcare systems to deliver custom insights from EMRs that help support ongoing observational and RWD research.
  • We can even contribute to protocol design and cohort suggestions.
Study Feasibility

Optimize study protocols and predict enrollment potential

Leverage AI-driven insights to design trials that are efficient, effective, and aligned with real-world data. Dyania’s in-house clinical team will analyze trial criteria to provide organizations with insights on whether specific trial sites have enough patient populations to support a given study, allowing them to make data-driven decisions.

  • ​Custom reports—delivered to key internal stakeholders—facilitate data-driven decision-making and expedite clinical trials.
Evidence-Guided Care Pathways

Get the best care available, flagged for the exact clinical characteristics a patient has—even if they are seeing providers across your enterprise

In a large health system with thousands of providers and millions of patients, we help health systems treat each patient individually at scale, where it would not be humanly possible. Synapsis AI takes numbers and data and turns that into opportunities to get patients the care they need. These can be patients who:

  • Have with a specific set of medical needs
  • Have presented with certain clinical characteristics for which they could benefit from a specific therapy
  • Have presented with high risk factors for an undiagnosed condition
  • Might receive more appropriate care from a specialist if they are referred exactly when they need it

A challenging use case:

~100,000 people in the U.S live with
ATTR-cardiomyopathy (ATTR-CM)

Only 1-2% of patients receive
a diagnosis

Identifying candidates from an under-diagnosed rare disease area

Transthyretin amyloidosis (ATTR) is a rare and potentially life-threatening disease caused by the abnormal buildup of amyloid fibrils composed of transthyretin (TTR) protein. This condition primarily affects the heart muscle, resembling other diseases like congestive heart failure, making it notoriously difficult to diagnose.

Despite an estimated 100,000 people in the U.S. living with ATTR-cardiomyopathy (ATTR-CM)—a subset of ATTR—only 1-2% of patients receive a diagnosis, highlighting a critical challenge in identifying and treating this underdiagnosed condition.

 

Synapsis AIin action

Dyania’s Patient Finder™, powered by Synapsis AI, delivered game-changing results for Cleveland Clinic. Here are the results for one Phase III, randomized ATTR-CM study in just the first week after Patient Finder™ launch:

Cleveland Clinic

30 patients identified as either “complete” or “high partial” matches for the trial in the first two weeks

35% more diverse patients identified compared to manual chart review

97% of these patients had been missed during previous manual screening efforts

These results show the transformative potential of Synapsis AI to address critical gaps in patient identification, enabling healthcare systems and pharmaceutical companies to accelerate clinical trials and bring life-saving treatments to market faster.

Through our work together with Dyania and the clinical leadership of Cleveland Clinic’s Heart, Vascular and Thoracic Institute and Cancer Institute, we are seeing early success with the technology in streamlining and accelerating the clinical trial recruitment process.

Cleveland Clinic

Rohit Chandra, PhD
Cleveland Clinic’s Chief Digital Officer

How to bring Synapsis AI to your organization:

Healthcare systems (HCS) can start deploying Synapsis AI as a commercially-scalable solution within months. The simple, streamlined process is a collaborative effort between Dyania physicians, Dyania engineers, and HCS leadership and IT professionals.

Business Agreement

01
We collaborate with health system leadership to pinpoint specific nuances and use cases where chart review creates bottlenecks. We set up the appropriate business and service agreements to ensure secure access to protected health information.

Protocol Scoping & Clinical Reasoning Engine Activation

02
Our in-house clinical team analyzes study protocols and prepares Synapsis AI for deployment.

One-Time Deployment

03
We install Synapsis AI within your healthcare system’s firewall. Secure access for all teams is granted via a VPN tunnel. Synapsis AI seamlessly integrates with any EMR database structure and is mapped to the clinical relevance of each data type, leading to minimal workflow disruption.

Data Ingestion

04
Synapsis AI ingests and structures vast quantities of EMR data, making assessments with the clinical reasoning of a trained physician.

Insights Generation

05
Our proprietary AI system analyzes patient records exponentially faster, extracting actionable insights tailored to your needs.

Delivery

06
We deliver insights through intuitive, modular dashboards tailored to your specific applications, enabling you to act quickly and confidently.

Ready to revolutionize your approach to clinical research and quality of care?

Contact us today to schedule a demo and learn how Synapsis AI can transform your healthcare operations.

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